| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa0246 | dsbA | PSHAa0246 | PSHAa0248 | Homologs of previously reported genes of unknown function; carrier. | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | 0.763 |
| PSHAa0246 | porA | PSHAa0246 | PSHAa0249 | Homologs of previously reported genes of unknown function; carrier. | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | 0.744 |
| PSHAa0246 | rdoA | PSHAa0246 | PSHAa0247 | Homologs of previously reported genes of unknown function; carrier. | Conserved hypothetical protein, putative homoserine kinase type II; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. | 0.795 |
| PSHAa2729 | ftsB | PSHAa2729 | PSHAa0683 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Putative cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.541 |
| PSHAa2729 | porA | PSHAa2729 | PSHAa0249 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | 0.571 |
| PSHAa2729 | rlpB | PSHAa2729 | PSHAa1030 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Putative minor lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.647 |
| bamE | dsbA | PSHAa0844 | PSHAa0248 | Conserved protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | 0.597 |
| bamE | dsbB | PSHAa0844 | PSHAa0837 | Conserved protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Disulfide bond formation protein B (Disulfide oxidoreductase); Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | 0.530 |
| bamE | ftsB | PSHAa0844 | PSHAa0683 | Conserved protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.739 |
| bamE | porA | PSHAa0844 | PSHAa0249 | Conserved protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | 0.666 |
| bamE | rlpB | PSHAa0844 | PSHAa1030 | Conserved protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative minor lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.843 |
| bamE | surA | PSHAa0844 | PSHAa2633 | Conserved protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Peptidyl-prolyl cis-trans isomerase (PPIase); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.941 |
| dsbA | PSHAa0246 | PSHAa0248 | PSHAa0246 | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | Homologs of previously reported genes of unknown function; carrier. | 0.763 |
| dsbA | bamE | PSHAa0248 | PSHAa0844 | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | Conserved protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.597 |
| dsbA | dsbB | PSHAa0248 | PSHAa0837 | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | Disulfide bond formation protein B (Disulfide oxidoreductase); Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | 0.983 |
| dsbA | ftsB | PSHAa0248 | PSHAa0683 | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | Putative cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.436 |
| dsbA | porA | PSHAa0248 | PSHAa0249 | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | 0.985 |
| dsbA | rdoA | PSHAa0248 | PSHAa0247 | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | Conserved hypothetical protein, putative homoserine kinase type II; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. | 0.882 |
| dsbA | rlpB | PSHAa0248 | PSHAa1030 | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | Putative minor lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.519 |
| dsbA | surA | PSHAa0248 | PSHAa2633 | Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. | Peptidyl-prolyl cis-trans isomerase (PPIase); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.557 |