Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa0261Putative FxsA protein (Suppressor of F exclusion of phage T7); Function of homologous gene experimentally demonstrated in an other organism; membrane component. (158 aa)    
Predicted Functional Partners:
hslV
Peptidase component of the HslUV protease; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
    0.832
PSHAa2342
Putative thioredoxin-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
   
    0.830
cutA
Periplasmic divalent cation tolerance protein (C-type cytochrome biogenesis protein); Function of strongly homologous gene.
     
 0.821
dipZ
Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
     
 0.753
groS
10 kDa chaperonin (Protein Cpn10) (groES protein); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
  
 0.641
PSHAa0614
Homologs of previously reported genes of unknown function; enzyme.
  
  
 0.580
htpX
Zinc metalloprotease HtpX, membrane-bound with cytosolic active site; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase M48B family.
   
  
 0.580
PSHAa1856
Homologs of previously reported genes of unknown function.
  
  
 0.580
hslU
ATPase component of the HslUV protease, also functions as molecular chaperone; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
   
    0.558
groL
60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
    0.518
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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