| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1210 | aroQ | PSHAa1210 | PSHAa0264 | Putative response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator. | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.488 |
| accB | accC | PSHAa0265 | PSHAa0266 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.999 |
| accB | aroQ | PSHAa0265 | PSHAa0264 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.902 |
| accB | cutA | PSHAa0265 | PSHAa0262 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Periplasmic divalent cation tolerance protein (C-type cytochrome biogenesis protein); Function of strongly homologous gene. | 0.754 |
| accB | dipZ | PSHAa0265 | PSHAa0263 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.743 |
| accB | rplM | PSHAa0265 | PSHAa2532 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.648 |
| accC | accB | PSHAa0266 | PSHAa0265 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.999 |
| accC | aroQ | PSHAa0266 | PSHAa0264 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.829 |
| accC | cutA | PSHAa0266 | PSHAa0262 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Periplasmic divalent cation tolerance protein (C-type cytochrome biogenesis protein); Function of strongly homologous gene. | 0.682 |
| accC | dipZ | PSHAa0266 | PSHAa0263 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.717 |
| aroB | aroE | PSHAa2714 | PSHAa0031 | Dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 5-dehydroshikimate reductase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.963 |
| aroB | aroQ | PSHAa2714 | PSHAa0264 | Dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.983 |
| aroE | aroB | PSHAa0031 | PSHAa2714 | 5-dehydroshikimate reductase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.963 |
| aroE | aroQ | PSHAa0031 | PSHAa0264 | 5-dehydroshikimate reductase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.955 |
| aroQ | PSHAa1210 | PSHAa0264 | PSHAa1210 | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Putative response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator. | 0.488 |
| aroQ | accB | PSHAa0264 | PSHAa0265 | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.902 |
| aroQ | accC | PSHAa0264 | PSHAa0266 | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.829 |
| aroQ | aroB | PSHAa0264 | PSHAa2714 | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.983 |
| aroQ | aroE | PSHAa0264 | PSHAa0031 | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 5-dehydroshikimate reductase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.955 |
| aroQ | cutA | PSHAa0264 | PSHAa0262 | 3-dehydroquinate dehydratase (EC 4.2.1.10) (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Periplasmic divalent cation tolerance protein (C-type cytochrome biogenesis protein); Function of strongly homologous gene. | 0.719 |