Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
amiBN-acetylmuramoyl-l-alanine amidase II, murein hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (431 aa)    
Predicted Functional Partners:
PSHAa0365
Homologs of previously reported genes of unknown function.
 
 
 
 0.930
miaA
Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
   
 0.913
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
  
 0.898
PSHAa0544
Putative peptidase, M23/M37 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
   
 0.824
PSHAa0267
Homologs of previously reported genes of unknown function; enzyme.
  
 
 0.792
hfq
Host factor-I; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
     
 0.748
guaA
GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
     
 0.743
hflX
HflX, putative GTPase subunit of protease with nucleoside triP hydrolase domain; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
     
 0.737
mltD
Putative membrane-bound lytic murein transglycosylase D [Precursor]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
  
 0.700
PSHAa0522
Homologs of previously reported genes of unknown function.
  
  
 0.636
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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