| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| degQ | glpF | PSHAa2536 | PSHAb0552 | Periplasmic serine endoprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S1C family. | Putative glycerol diffusion channel; Function of strongly homologous gene; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.562 |
| degQ | grpE | PSHAa2536 | PSHAa1222 | Periplasmic serine endoprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S1C family. | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | 0.578 |
| degQ | hflC | PSHAa2536 | PSHAa0274 | Periplasmic serine endoprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S1C family. | HflC; HflC and HflK could regulate a protease. | 0.744 |
| degQ | hflK | PSHAa2536 | PSHAa0273 | Periplasmic serine endoprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S1C family. | HflK complex with HflC; HflC and HflK could encode or regulate a protease. | 0.742 |
| ftsH | grpE | PSHAa0870 | PSHAa1222 | Cell division protease ftsH, ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | 0.704 |
| ftsH | hflC | PSHAa0870 | PSHAa0274 | Cell division protease ftsH, ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | HflC; HflC and HflK could regulate a protease. | 0.948 |
| ftsH | hflK | PSHAa0870 | PSHAa0273 | Cell division protease ftsH, ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | HflK complex with HflC; HflC and HflK could encode or regulate a protease. | 0.972 |
| ftsH | hflX | PSHAa0870 | PSHAa0272 | Cell division protease ftsH, ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | HflX, putative GTPase subunit of protease with nucleoside triP hydrolase domain; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.605 |
| ftsH | hflX-2 | PSHAa0870 | PSHAa1393 | Cell division protease ftsH, ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative GTP binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.605 |
| ftsH | hfq | PSHAa0870 | PSHAa0271 | Cell division protease ftsH, ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Host factor-I; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.616 |
| ftsH | miaA | PSHAa0870 | PSHAa0270 | Cell division protease ftsH, ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.460 |
| ftsH | yidC | PSHAa0870 | PSHAa3022 | Cell division protease ftsH, ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Preprotein translocase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.460 |
| glpF | degQ | PSHAb0552 | PSHAa2536 | Putative glycerol diffusion channel; Function of strongly homologous gene; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Periplasmic serine endoprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S1C family. | 0.562 |
| glpF | grpE | PSHAb0552 | PSHAa1222 | Putative glycerol diffusion channel; Function of strongly homologous gene; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | 0.409 |
| glpF | hflC | PSHAb0552 | PSHAa0274 | Putative glycerol diffusion channel; Function of strongly homologous gene; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | HflC; HflC and HflK could regulate a protease. | 0.693 |
| glpF | hflK | PSHAb0552 | PSHAa0273 | Putative glycerol diffusion channel; Function of strongly homologous gene; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | HflK complex with HflC; HflC and HflK could encode or regulate a protease. | 0.693 |
| grpE | degQ | PSHAa1222 | PSHAa2536 | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | Periplasmic serine endoprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S1C family. | 0.578 |
| grpE | ftsH | PSHAa1222 | PSHAa0870 | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | Cell division protease ftsH, ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.704 |
| grpE | glpF | PSHAa1222 | PSHAb0552 | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | Putative glycerol diffusion channel; Function of strongly homologous gene; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.409 |
| grpE | hflC | PSHAa1222 | PSHAa0274 | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | HflC; HflC and HflK could regulate a protease. | 0.641 |
