Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa0364Putative carboxyl-terminal protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the peptidase S41A family. (421 aa)    
Predicted Functional Partners:
PSHAa0365
Homologs of previously reported genes of unknown function.
 
  
 0.903
gpmM
Phosphoglycerate mutase III, cofactor-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.804
nlpI
Lipoprotein probably involved in cell division after interaction with a protease; May be involved in cell division.
    
 
 0.782
PSHAa0363
Homologs of previously reported genes of unknown function.
       0.776
gpsA
Glycerol-3-phosphate dehydrogenase (NAD+); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.618
nudH
(Di)nucleoside polyphosphate hydrolase (Ap5A pyrophosphatase); Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
    
 0.603
PSHAa0367
Homologs of previously reported genes of unknown function.
  
    0.528
PSHAa0368
Glutaredoxin 3 GrxC; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
     
 0.515
secB
Molecular chaperone in protein export, enhances activity of SecA (General Secretory Pathway); One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
       0.512
oadA
Oxaloacetate decarboxylase, alpha subunit; Function of strongly homologous gene; enzyme.
  
    0.499
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: medium (42%) [HD]