Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pilCType IV pilus biogenesis protein PilC; Function of homologous gene experimentally demonstrated in an other organism; membrane component. (408 aa)    
Predicted Functional Partners:
pilD
Type 4 prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.975
pilB
Type IV pilus biogenesis protein PilB; Function of homologous gene experimentally demonstrated in an other organism.
 
 0.965
exeE
General secretion pathway protein E (Type II traffic warden ATPase); Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
 0.928
mshE
Putative Mannose-sensitive agglutinin (MSHA) biogenesis protein MshE (pilus type IV); Function of strongly homologous gene; 11985966.
 
 0.928
gspG
Putative general secretion pathway protein G [Precursor]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
 
  
 0.880
pilM
Putative Type IV pilus biogenesis protein PilM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; structural protein.
 
 
 
 0.821
pilT
Twitching motility protein PilT (type IV pili); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.817
pilU
Twitching motility protein PilU (type IV pili); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.807
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.800
pilQ
Putative type IV pilus biogenesis protein PilQ (cytoplasmic ATPase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
 
 
 0.797
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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