Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa0443Putative RNAse with metallo-beta-lactamase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. (474 aa)    
Predicted Functional Partners:
gpmM
Phosphoglycerate mutase III, cofactor-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.898
PSHAa2902
Homologs of previously reported genes of unknown function; 11347268, 14672542.
    
 0.894
apaH
Diadenosine tetraphosphatase (Ap4A hydrolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.859
PSHAa0253
Homologs of previously reported genes of unknown function.
   
 0.697
PSHAa1018
Homologs of previously reported genes of unknown function.
   
 0.697
PSHAa1401
Putative enzyme with metallo-hydrolase/oxidoreductase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
     
 0.580
polA
Multifunctional DNA polymerase I: 5'->3' exonuclease (N-terminal); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.571
sbcD
Exonuclease sbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.540
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.527
PSHAa2177
Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
   
 0.499
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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