Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dusAtRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (310 aa)    
Predicted Functional Partners:
sdaA
L-serine deaminase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family.
   
  
 0.826
pspA
Putative negative regulatory gene for the psp operon, phage shock protein A; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator.
       0.704
cysE
Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
   
 0.687
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
      0.678
umuD
Component of DNA polymerase V; Function of strongly homologous gene; enzyme; Belongs to the peptidase S24 family.
      
 0.660
dam
DNA adenine methylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.651
tolC
Outer membrane protein tolC precursor; Function of homologous gene experimentally demonstrated in an other organism; transporter.
      
 0.630
truB
tRNA pseudouridine 5S synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
  
 0.594
trmJ
Putative tRNA/rRNA methyltransferase (trmH family); Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
  
   
 0.581
pspC
Putative phage shock protein C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
       0.506
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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