| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1662 | recG | PSHAa1662 | PSHAa2799 | Competence protein ComEC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.445 |
| PSHAa1662 | recJ | PSHAa1662 | PSHAa0516 | Competence protein ComEC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Single-stranded-DNA-specific exonuclease, 5'--> 3'-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.648 |
| PSHAa1662 | xseA | PSHAa1662 | PSHAa0647 | Competence protein ComEC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Exonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.494 |
| PSHAa2008 | recJ | PSHAa2008 | PSHAa0516 | Putative orphan protein; No homology to any previously reported sequences. | Single-stranded-DNA-specific exonuclease, 5'--> 3'-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.732 |
| PSHAb0119 | mutL | PSHAb0119 | PSHAa0269 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.680 |
| PSHAb0119 | recG | PSHAb0119 | PSHAa2799 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.537 |
| PSHAb0119 | recJ | PSHAb0119 | PSHAa0516 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Single-stranded-DNA-specific exonuclease, 5'--> 3'-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.911 |
| PSHAb0119 | recQ | PSHAb0119 | PSHAa2572 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.923 |
| dsbC | recJ | PSHAa0515 | PSHAa0516 | Disulfide bond isomerase, periplasmic; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | Single-stranded-DNA-specific exonuclease, 5'--> 3'-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.830 |
| dsbC | xerD | PSHAa0515 | PSHAa0514 | Disulfide bond isomerase, periplasmic; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | Site-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.782 |
| mutL | PSHAb0119 | PSHAa0269 | PSHAb0119 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.680 |
| mutL | radA | PSHAa0269 | PSHAa0663 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Putative DNA repair protein radA (DNA repair protein sms); DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.502 |
| mutL | recG | PSHAa0269 | PSHAa2799 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.629 |
| mutL | recJ | PSHAa0269 | PSHAa0516 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Single-stranded-DNA-specific exonuclease, 5'--> 3'-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.774 |
| mutL | recQ | PSHAa0269 | PSHAa2572 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.680 |
| mutL | xseA | PSHAa0269 | PSHAa0647 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Exonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.570 |
| radA | mutL | PSHAa0663 | PSHAa0269 | Putative DNA repair protein radA (DNA repair protein sms); DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.502 |
| radA | recG | PSHAa0663 | PSHAa2799 | Putative DNA repair protein radA (DNA repair protein sms); DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.614 |
| radA | recJ | PSHAa0663 | PSHAa0516 | Putative DNA repair protein radA (DNA repair protein sms); DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Single-stranded-DNA-specific exonuclease, 5'--> 3'-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.646 |
| radA | xseA | PSHAa0663 | PSHAa0647 | Putative DNA repair protein radA (DNA repair protein sms); DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Exonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.474 |
