Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PSHAa0522Homologs of previously reported genes of unknown function. (553 aa)    
Predicted Functional Partners:
PSHAa0521
Homologs of previously reported genes of unknown function.
    0.995
nagZ
Beta-hexosaminidase A (N-acetyl-beta-glucosaminidase) (Beta-N-acetylhexosaminidase) (Chitobiase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glycosyl hydrolase 3 family.
  
 0.984
mrcB
Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
   
 
 0.929
mrdA
Cell elongation-specific transpeptidase of penicillin-binding protein 2 (peptidoglycan synthetase); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
    
 0.928
ftsI
Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
    
 0.928
dacA
D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S11 family.
    
 0.927
mrcA
Penicillin-binding protein 1A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.926
anmK
Putative molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
   
 0.671
amiB
N-acetylmuramoyl-l-alanine amidase II, murein hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.636
mltD
Putative membrane-bound lytic murein transglycosylase D [Precursor]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
     
 0.608
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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