node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSHAa0600 | folK | PSHAa0600 | PSHAa0603 | Putative orphan protein; No homology to any previously reported sequences. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.822 |
PSHAa0600 | panB | PSHAa0600 | PSHAa0602 | Putative orphan protein; No homology to any previously reported sequences. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.853 |
PSHAa0600 | panC | PSHAa0600 | PSHAa0601 | Putative orphan protein; No homology to any previously reported sequences. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.853 |
PSHAa0600 | pcnB | PSHAa0600 | PSHAa0604 | Putative orphan protein; No homology to any previously reported sequences. | poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.822 |
PSHAa2279 | panB | PSHAa2279 | PSHAa0602 | Putative 2-dehydropantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.975 |
PSHAa2279 | panC | PSHAa2279 | PSHAa0601 | Putative 2-dehydropantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.969 |
folK | PSHAa0600 | PSHAa0603 | PSHAa0600 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative orphan protein; No homology to any previously reported sequences. | 0.822 |
folK | panB | PSHAa0603 | PSHAa0602 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.966 |
folK | panC | PSHAa0603 | PSHAa0601 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.898 |
folK | pcnB | PSHAa0603 | PSHAa0604 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.989 |
ilvD | ilvD2 | PSHAa2769 | PSHAb0129 | Dihydroxyacid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family. | Putative dihydroxyacid dehydratase (ilvD-like); Function of strongly homologous gene; enzyme; Belongs to the IlvD/Edd family. | 0.909 |
ilvD | ilvE | PSHAa2769 | PSHAa1270 | Dihydroxyacid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family. | Putative branched-chain amino acid aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.975 |
ilvD | panB | PSHAa2769 | PSHAa0602 | Dihydroxyacid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.911 |
ilvD2 | ilvD | PSHAb0129 | PSHAa2769 | Putative dihydroxyacid dehydratase (ilvD-like); Function of strongly homologous gene; enzyme; Belongs to the IlvD/Edd family. | Dihydroxyacid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family. | 0.909 |
ilvD2 | ilvE | PSHAb0129 | PSHAa1270 | Putative dihydroxyacid dehydratase (ilvD-like); Function of strongly homologous gene; enzyme; Belongs to the IlvD/Edd family. | Putative branched-chain amino acid aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.975 |
ilvD2 | panB | PSHAb0129 | PSHAa0602 | Putative dihydroxyacid dehydratase (ilvD-like); Function of strongly homologous gene; enzyme; Belongs to the IlvD/Edd family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.911 |
ilvE | ilvD | PSHAa1270 | PSHAa2769 | Putative branched-chain amino acid aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Dihydroxyacid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family. | 0.975 |
ilvE | ilvD2 | PSHAa1270 | PSHAb0129 | Putative branched-chain amino acid aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative dihydroxyacid dehydratase (ilvD-like); Function of strongly homologous gene; enzyme; Belongs to the IlvD/Edd family. | 0.975 |
ilvE | panB | PSHAa1270 | PSHAa0602 | Putative branched-chain amino acid aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.918 |
panB | PSHAa0600 | PSHAa0602 | PSHAa0600 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Putative orphan protein; No homology to any previously reported sequences. | 0.853 |