Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa0629Homologs of previously reported genes of unknown function. (244 aa)    
Predicted Functional Partners:
PSHAa0631
Putative transpeptidase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
    0.862
PSHAa0183
Putative outer membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
  
     0.744
tolB
Required for outer membrane integrity, uptake of group A colicins, and translocation of phage DNA; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.727
PSHAa0627
Putative sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
 
   
 0.720
pal
Required for outer membrane integrity, uptake of group A colicins, and translocation of phage DNA; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
     0.706
PSHAa0630
Homologs of previously reported genes of unknown function.
       0.686
PSHAa0628
Homologs of previously reported genes of unknown function.
 
  
 0.648
cpoB
Putative periplasmic protein contains a protein prenylyltransferase domain; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
 
  
 0.569
flgE
Flagellar biosynthesis; Function of strongly homologous gene; structural protein.
   
 
 0.559
lolC
Transport protein of outer membrane lipoproteins (ABC superfamily, membrane); Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
 
 
 0.551
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: low (20%) [HD]