STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
proB-2Glutamate-5 kinase(Gamma-glutamyl kinase)(GK); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa)    
Predicted Functional Partners:
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 0.999
putA
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
 0.945
proB
Putative glutamate 5-kinase (Gamma-glutamyl kinase); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
  
  
 
0.915
proC
Pyrroline-5-carboxylate reductase (NAD(P)-binding); Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 0.875
gltB
Glutamate synthase, large subunit, GOGAT; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.584
PSHAa0632
Homologs of previously reported genes of unknown function.
       0.553
PSHAa0634
Putative Glutaredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
       0.490
prs
Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
    
 0.482
argB
Acetylglutamate kinase (NAG kinase) (AGK) (N-acetyl-L-glutamate 5-phosphotransferase); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
   
 0.425
gltX
Glutamyl-tRNA synthetase (Glutamate-tRNA ligase); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.409
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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