STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rseAPutative anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), wh [...] (205 aa)    
Predicted Functional Partners:
rseB
Putative anti sigma E (sigma 24) factor, negative regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; factor.
 
 
 0.998
rpoE
RNA polymerase sigma-70 factor, ECF subfamily; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.991
rseC
Putative regulator of sigma E (sigma 24) factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; factor.
 
  
 0.932
PSHAa1826
Putative sigma factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.929
PSHAa2438
Putative RNA polymerase sigma factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.846
sigY
Putative RNA polymerase sigma factor, ECF subfamily, response to stress; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.846
sigW
Putative RNA polymerase sigma factor (ECF family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.826
PSHAa0959
RNA polymerase sigma factor; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.812
degQ
Periplasmic serine endoprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S1C family.
  
 
 0.802
degS
Periplasmic serine endoprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.802
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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