Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccmECytochrome c-type biogenesis protein ccmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (159 aa)    
Predicted Functional Partners:
ccmC
Heme exporter protein C (Cytochrome c-type biogenesis protein ccmC); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.999
ccmB
Heme exporter protein B, ABC superfamily (Cytochrome c-type biogenesis protein ccmB); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
 
 0.998
ccmA
Heme exporter protein A, ABC superfamily (Cytochrome c-type biogenesis ATP-binding protein ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
 
 0.997
ccmD
Heme exporter protein D (Cytochrome c-type biogenesis protein ccmD); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
 
 
 0.995
ccmF
Cytochrome c-type biogenesis protein ccmF; Function of homologous gene experimentally demonstrated in an other organism; carrier.
 
 
 0.989
ccmG
Thiol:disulfide interchange protein dsbE (cytochrome c biogenesis protein ccmG); Function of strongly homologous gene; enzyme.
 
  
 0.988
ccmH
Cytochrome c-type biogenesis protein CcmH; Possible subunit of a heme lyase.
 
  
 0.984
PSHAa0830
Putative cytochrome c-type biogenesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
 
  
 0.977
vacJ
Lipoprotein precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component.
 
     0.881
PSHAa0820
Homologs of previously reported genes of unknown function.
       0.742
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.