| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa0842 | guaA | PSHAa0842 | PSHAa0649 | Homologs of previously reported genes of unknown function. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.476 |
| PSHAa0842 | rnfH | PSHAa0842 | PSHAa0843 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | 0.960 |
| PSHAa0842 | smpB | PSHAa0842 | PSHAa0841 | Homologs of previously reported genes of unknown function. | SsrA-binding protein (small protein B); Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosom [...] | 0.763 |
| cca | rnfH | PSHAa0625 | PSHAa0843 | tRNA nucleotidyl transferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | 0.534 |
| guaA | PSHAa0842 | PSHAa0649 | PSHAa0842 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Homologs of previously reported genes of unknown function. | 0.476 |
| guaA | rnfH | PSHAa0649 | PSHAa0843 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | 0.493 |
| guaA | smpB | PSHAa0649 | PSHAa0841 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | SsrA-binding protein (small protein B); Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosom [...] | 0.540 |
| rnfH | PSHAa0842 | PSHAa0843 | PSHAa0842 | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | Homologs of previously reported genes of unknown function. | 0.960 |
| rnfH | cca | PSHAa0843 | PSHAa0625 | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | tRNA nucleotidyl transferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.534 |
| rnfH | guaA | PSHAa0843 | PSHAa0649 | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.493 |
| rnfH | rsxA | PSHAa0843 | PSHAa1105 | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | Electron transport complex protein rnfA, inner membrane protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | 0.965 |
| rnfH | rsxB | PSHAa0843 | PSHAa1104 | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | Electron transport complex protein rnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. | 0.956 |
| rnfH | rsxC | PSHAa0843 | PSHAa1103 | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | Electron transport complex protein rnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | 0.984 |
| rnfH | rsxD | PSHAa0843 | PSHAa1102 | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | Electron transport complex protein rnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. | 0.918 |
| rnfH | rsxE | PSHAa0843 | PSHAa1100 | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | Electron transport complex protein rnfE; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | 0.853 |
| rnfH | rsxG | PSHAa0843 | PSHAa1101 | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | Electron transport complex protein rnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. | 0.929 |
| rnfH | smpB | PSHAa0843 | PSHAa0841 | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | SsrA-binding protein (small protein B); Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosom [...] | 0.762 |
| rsxA | rnfH | PSHAa1105 | PSHAa0843 | Electron transport complex protein rnfA, inner membrane protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | Homologs of previously reported genes of unknown function; Belongs to the UPF0125 (RnfH) family. | 0.965 |
| rsxA | rsxB | PSHAa1105 | PSHAa1104 | Electron transport complex protein rnfA, inner membrane protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | Electron transport complex protein rnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. | 0.999 |
| rsxA | rsxC | PSHAa1105 | PSHAa1103 | Electron transport complex protein rnfA, inner membrane protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | Electron transport complex protein rnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | 0.999 |