| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa2301 | folB | PSHAa2301 | PSHAa2302 | Putative phosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.994 |
| PSHAa2301 | folC | PSHAa2301 | PSHAa2073 | Putative phosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Bifunctional: folylpolyglutamate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family. | 0.467 |
| PSHAa2301 | folE | PSHAa2301 | PSHAa0073 | Putative phosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | GTP cyclohydrolase I; Function of strongly homologous gene; enzyme. | 0.812 |
| PSHAa2301 | folK | PSHAa2301 | PSHAa0603 | Putative phosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.926 |
| PSHAa2301 | folP | PSHAa2301 | PSHAa0871 | Putative phosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.994 |
| folB | PSHAa2301 | PSHAa2302 | PSHAa2301 | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative phosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.994 |
| folB | folC | PSHAa2302 | PSHAa2073 | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional: folylpolyglutamate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family. | 0.525 |
| folB | folE | PSHAa2302 | PSHAa0073 | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; Function of strongly homologous gene; enzyme. | 0.857 |
| folB | folK | PSHAa2302 | PSHAa0603 | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.980 |
| folB | folP | PSHAa2302 | PSHAa0871 | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.987 |
| folC | PSHAa2301 | PSHAa2073 | PSHAa2301 | Bifunctional: folylpolyglutamate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family. | Putative phosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.467 |
| folC | folB | PSHAa2073 | PSHAa2302 | Bifunctional: folylpolyglutamate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.525 |
| folC | folE | PSHAa2073 | PSHAa0073 | Bifunctional: folylpolyglutamate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I; Function of strongly homologous gene; enzyme. | 0.621 |
| folC | folK | PSHAa2073 | PSHAa0603 | Bifunctional: folylpolyglutamate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.603 |
| folC | folP | PSHAa2073 | PSHAa0871 | Bifunctional: folylpolyglutamate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.997 |
| folE | PSHAa2301 | PSHAa0073 | PSHAa2301 | GTP cyclohydrolase I; Function of strongly homologous gene; enzyme. | Putative phosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.812 |
| folE | folB | PSHAa0073 | PSHAa2302 | GTP cyclohydrolase I; Function of strongly homologous gene; enzyme. | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.857 |
| folE | folC | PSHAa0073 | PSHAa2073 | GTP cyclohydrolase I; Function of strongly homologous gene; enzyme. | Bifunctional: folylpolyglutamate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family. | 0.621 |
| folE | folK | PSHAa0073 | PSHAa0603 | GTP cyclohydrolase I; Function of strongly homologous gene; enzyme. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.993 |
| folE | folP | PSHAa0073 | PSHAa0871 | GTP cyclohydrolase I; Function of strongly homologous gene; enzyme. | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.978 |