STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa0958Homologs of previously reported genes of unknown function. (251 aa)    
Predicted Functional Partners:
PSHAa0959
RNA polymerase sigma factor; Function of strongly homologous gene; factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.901
PSHAa0960
Homologs of previously reported genes of unknown function.
  
    0.823
PSHAa0962
Homologs of previously reported genes of unknown function.
       0.822
PSHAa0964
Homologs of previously reported genes of unknown function.
       0.822
PSHAa0963
Putative orphan protein; No homology to any previously reported sequences.
       0.816
PSHAa0965
Putative ATPase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
       0.757
rseA
Putative anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), wh [...]
  
 
 0.755
PSHAa0961
Homologs of previously reported genes of unknown function.
       0.661
fadJ
Fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family. In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
     
 0.628
fadI
Beta-keto thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
       0.611
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.