Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa0988Homologs of previously reported genes of unknown function. (91 aa)    
Predicted Functional Partners:
PSHAa0987
Homologs of previously reported genes of unknown function.
      0.933
PSHAa0986
Homologs of previously reported genes of unknown function.
  
    0.828
PSHAa2535
Homologs of previously reported genes of unknown function.
  
     0.745
yihI
Conserved protein of unknown function; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.719
PSHAa0989
Putative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
       0.693
seqA
SeqA protein, recognizes hemimethylated GATC motifs; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.688
PSHAa1896
Homologs of previously reported genes of unknown function.
  
     0.655
arcB
Aerobic respiration control sensor protein arcB; Function of strongly homologous gene; regulator.
  
     0.650
PSHAa1818
Homologs of previously reported genes of unknown function; Belongs to the UPF0352 family.
  
     0.643
bamC
Putative lipoprotein-34 NlpB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.642
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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