STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa1010Putative Zn(II)-responsive transcriptional regulator, regulates Zn export (MerR family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator. (144 aa)    
Predicted Functional Partners:
copAB
P-type ATPase, copper transporting, phophatase-like domain; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
  
 0.899
PSHAa1012
Putative orphan protein; No homology to any previously reported sequences.
 
     0.806
PSHAa0654
Homologs of previously reported genes of unknown function.
   
 
 0.793
PSHAa2621
Putative Sensory box sensor histidine kinase/response regulator; Function of strongly homologous gene; receptor.
   
 
 0.790
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.673
PSHAa1453
Putative Transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator.
  
   
 0.618
PSHAb0289
Putative two-component hybrid sensor and regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator.
   
 
 0.565
PSHAa0110
Putative DnaJ-class molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; molecular chaperone.
  
 
 0.551
cbpA
Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone.
  
 
 0.551
dnaJ
Chaperone protein dnaJ (Heat shock protein J) (HSP40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...]
  
 
 0.551
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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