STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
holAPutative DNA polymerase III, delta subunit, probably ATP hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. (345 aa)    
Predicted Functional Partners:
holB
Putative DNA polymerase III delta' subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
    
 0.998
dnaE
DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.998
holC
DNA polymerase III, chi subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.997
dnaN
DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.995
PSHAa1201
Putative DnaX, DNA polymerase III, gamma/tau subunits; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
   
 0.994
dnaQ
DNA polymerase III: epsilon subunit, 3-5 exonucleolytic proofreading function; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
    
 0.971
leuS
leucyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.
      0.930
PSHAa0589
Putative DNA polymerase, exonuclease activity; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
    
 0.929
PSHAa1435
Putative DNA polymerase III, epsilon subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
    
 0.929
PSHAa1996
Homologs of previously reported genes of unknown function; enzyme.
    
 0.929
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.