node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSHAa1138 | gcvP | PSHAa1138 | PSHAa2473 | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Glycine cleavage complex protein P, glycine decarboxylase, PLP-dependent; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.436 |
PSHAa1138 | miaB | PSHAa1138 | PSHAa1046 | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.506 |
PSHAa1138 | rplK | PSHAa1138 | PSHAa0218 | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.448 |
PSHAa1138 | rplQ | PSHAa1138 | PSHAa2805 | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 50S ribosomal protein L17; Function of homologous gene experimentally demonstrated in an other organism; structural protein. | 0.490 |
PSHAa1138 | rplU | PSHAa1138 | PSHAa2656 | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.518 |
PSHAa1138 | rpsQ | PSHAa1138 | PSHAa0153 | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.955 |
PSHAa1138 | sodB | PSHAa1138 | PSHAa1215 | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Iron superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.831 |
PSHAa1138 | ybeY | PSHAa1138 | PSHAa1044 | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Conserved protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.973 |
corC | miaB | PSHAa1043 | PSHAa1046 | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.603 |
corC | ybeY | PSHAa1043 | PSHAa1044 | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | Conserved protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.920 |
corC | ybeZ | PSHAa1043 | PSHAa1045 | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | PhoH-like protein; Function of strongly homologous gene; transporter. | 0.836 |
gcvP | PSHAa1138 | PSHAa2473 | PSHAa1138 | Glycine cleavage complex protein P, glycine decarboxylase, PLP-dependent; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.436 |
gcvP | ybeY | PSHAa2473 | PSHAa1044 | Glycine cleavage complex protein P, glycine decarboxylase, PLP-dependent; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Conserved protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.844 |
miaB | PSHAa1138 | PSHAa1046 | PSHAa1138 | Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.506 |
miaB | corC | PSHAa1046 | PSHAa1043 | Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | 0.603 |
miaB | ybeY | PSHAa1046 | PSHAa1044 | Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Conserved protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.949 |
miaB | ybeZ | PSHAa1046 | PSHAa1045 | Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | PhoH-like protein; Function of strongly homologous gene; transporter. | 0.921 |
rplK | PSHAa1138 | PSHAa0218 | PSHAa1138 | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.448 |
rplK | rplQ | PSHAa0218 | PSHAa2805 | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 50S ribosomal protein L17; Function of homologous gene experimentally demonstrated in an other organism; structural protein. | 0.995 |
rplK | rplU | PSHAa0218 | PSHAa2656 | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.995 |