| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| clpX | hfq | PSHAa2061 | PSHAa0271 | ATPase, chaperone subunit of serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Host factor-I; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.872 |
| clpX | ybeZ | PSHAa2061 | PSHAa1045 | ATPase, chaperone subunit of serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | PhoH-like protein; Function of strongly homologous gene; transporter. | 0.670 |
| corC | cutE | PSHAa1043 | PSHAa1042 | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | Apolipoprotein N-acyltransferase copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.952 |
| corC | miaB | PSHAa1043 | PSHAa1046 | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.633 |
| corC | ubiF | PSHAa1043 | PSHAa1047 | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | 2-octoprenyl-3-methyl-6-methoxy-1, 4-benzoquinone hydroxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.545 |
| corC | ybeY | PSHAa1043 | PSHAa1044 | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | Conserved protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.963 |
| corC | ybeZ | PSHAa1043 | PSHAa1045 | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | PhoH-like protein; Function of strongly homologous gene; transporter. | 0.901 |
| cutE | corC | PSHAa1042 | PSHAa1043 | Apolipoprotein N-acyltransferase copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | 0.952 |
| cutE | miaB | PSHAa1042 | PSHAa1046 | Apolipoprotein N-acyltransferase copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.640 |
| cutE | ubiF | PSHAa1042 | PSHAa1047 | Apolipoprotein N-acyltransferase copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 2-octoprenyl-3-methyl-6-methoxy-1, 4-benzoquinone hydroxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.430 |
| cutE | ybeY | PSHAa1042 | PSHAa1044 | Apolipoprotein N-acyltransferase copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Conserved protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.802 |
| cutE | ybeZ | PSHAa1042 | PSHAa1045 | Apolipoprotein N-acyltransferase copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | PhoH-like protein; Function of strongly homologous gene; transporter. | 0.893 |
| era | recO | PSHAa0733 | PSHAa0734 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein recO (Recombination protein O); Involved in DNA repair and RecF pathway recombination. | 0.963 |
| era | ybeY | PSHAa0733 | PSHAa1044 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Conserved protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.744 |
| era | ybeZ | PSHAa0733 | PSHAa1045 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | PhoH-like protein; Function of strongly homologous gene; transporter. | 0.545 |
| hfq | clpX | PSHAa0271 | PSHAa2061 | Host factor-I; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | ATPase, chaperone subunit of serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.872 |
| hfq | ybeY | PSHAa0271 | PSHAa1044 | Host factor-I; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Conserved protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.476 |
| hfq | ybeZ | PSHAa0271 | PSHAa1045 | Host factor-I; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | PhoH-like protein; Function of strongly homologous gene; transporter. | 0.539 |
| miaB | corC | PSHAa1046 | PSHAa1043 | Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Magnesium and cobalt efflux protein corC; Function of strongly homologous gene; transporter. | 0.633 |
| miaB | cutE | PSHAa1046 | PSHAa1042 | Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Apolipoprotein N-acyltransferase copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.640 |