| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1084 | PSHAa1085 | PSHAa1084 | PSHAa1085 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.849 |
| PSHAa1084 | ligA | PSHAa1084 | PSHAa1083 | Homologs of previously reported genes of unknown function. | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.868 |
| PSHAa1084 | msrB | PSHAa1084 | PSHAa1087 | Homologs of previously reported genes of unknown function. | Peptide methionine-R-sulfoxide reductase, MsrB protein (PilB protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.586 |
| PSHAa1085 | PSHAa1084 | PSHAa1085 | PSHAa1084 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.849 |
| PSHAa1085 | ligA | PSHAa1085 | PSHAa1083 | Homologs of previously reported genes of unknown function. | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.863 |
| PSHAa1085 | msrB | PSHAa1085 | PSHAa1087 | Homologs of previously reported genes of unknown function. | Peptide methionine-R-sulfoxide reductase, MsrB protein (PilB protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.739 |
| PSHAa1896 | msrB | PSHAa1896 | PSHAa1087 | Homologs of previously reported genes of unknown function. | Peptide methionine-R-sulfoxide reductase, MsrB protein (PilB protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.958 |
| PSHAa1896 | msrC | PSHAa1896 | PSHAa1444 | Homologs of previously reported genes of unknown function. | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.831 |
| dipZ | mrsAB | PSHAa0263 | PSHAa1243 | Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Putative peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.486 |
| dipZ | msrAA | PSHAa0263 | PSHAa1583 | Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.486 |
| dipZ | msrAB | PSHAa0263 | PSHAa2274 | Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | protein-methionine-S-oxide reductase (Peptide Met(O) reductase); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.486 |
| dipZ | msrB | PSHAa0263 | PSHAa1087 | Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Peptide methionine-R-sulfoxide reductase, MsrB protein (PilB protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.600 |
| dipZ | msrC | PSHAa0263 | PSHAa1444 | Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.943 |
| ligA | PSHAa1084 | PSHAa1083 | PSHAa1084 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Homologs of previously reported genes of unknown function. | 0.868 |
| ligA | PSHAa1085 | PSHAa1083 | PSHAa1085 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Homologs of previously reported genes of unknown function. | 0.863 |
| ligA | msrB | PSHAa1083 | PSHAa1087 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Peptide methionine-R-sulfoxide reductase, MsrB protein (PilB protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.587 |
| mrsAB | dipZ | PSHAa1243 | PSHAa0263 | Putative peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.486 |
| mrsAB | msrB | PSHAa1243 | PSHAa1087 | Putative peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Peptide methionine-R-sulfoxide reductase, MsrB protein (PilB protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.985 |
| mrsAB | msrC | PSHAa1243 | PSHAa1444 | Putative peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.554 |
| msrAA | dipZ | PSHAa1583 | PSHAa0263 | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.486 |