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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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PSHAa1138Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. (752 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 0.994
sirA
Small ubiquitous RNA-binding protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.
  
 0.992
iscU
Fe-S assembly protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 0.976
nfuA
Conserved protein of unknown function; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.976
thiF
Putative adenylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
   
 0.974
sseA
Putative 3-mercaptopyruvate sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 0.972
iscS-2
Cysteine desulfurase (ThiI) (transpersulfidase) (NifS protein homolog); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
0.935
iscS
Cysteine desulfurase (tRNA sulfurtransferase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
 
0.932
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.917
PSHAb0393
Putative acyl carrier protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; carrier.
  
 
 0.917
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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