Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa1187Homologs of previously reported genes of unknown function. (256 aa)    
Predicted Functional Partners:
ExbB2
TonB system transport protein ExbB2; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
    0.973
PSHAa1188
MotA/TolQ/ExbB proton channel family protein; Function of homologous gene experimentally demonstrated in an other organism; transporter.
    0.971
TonB2
TonB2 protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
     0.949
PSHAa1192
Putative TPR domain protein (tetratricopeptide repeat); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; 9482716, 1882418.
 
   0.949
ExbD2
TonB system transport protein ExbD2; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
     0.941
PSHAb0521
Putative Tol protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
    0.807
PSHAb0525
Putative unknown membrane associated protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator.
 
   0.801
PSHAb0522
Putative TonB system-dependent transport protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
 
    0.793
PSHAb0524
Putative TonB2 protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
     0.789
PSHAb0523
Putative TonB system-dependent transport protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
 
     0.784
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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