STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (181 aa)    
Predicted Functional Partners:
guaA
GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
  
 0.996
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.967
purB
Adenylosuccinate lyase; Function of strongly homologous gene; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.958
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Function of strongly homologous gene; enzyme.
  
 0.955
adk
Adenylate kinase(ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.941
gsk
Inosine-guanosine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.938
deoD
Purine nucleoside phosphorylase (Inosine phosphorylase) (PNP); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.925
surE
Acid phosphatase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.912
PSHAa2167
Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
    
 0.911
ushA
Protein ushA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the 5'-nucleotidase family.
    
 0.911
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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