Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa1216Conserved protein of unknown function with thioredoxin-like domain; Homologs of previously reported genes of unknown function; Belongs to the glutaredoxin family. Monothiol subfamily. (112 aa)    
Predicted Functional Partners:
bolA
Regulator protein; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the BolA/IbaG family.
 
 
 0.919
nfuA
Conserved protein of unknown function; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.861
sodB
Iron superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.795
grxC
Glutaredoxin 3 (Grx3); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
 
 0.771
PSHAa0368
Glutaredoxin 3 GrxC; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
 
 0.713
PSHAa2539
Putative transcriptional regulator (BolA family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator; Belongs to the BolA/IbaG family.
 
 
 
 0.664
visC
Putative monooxygenase, FAD/NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
    0.646
erpA
Putative HesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 0.644
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.628
iscA
Iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.
 
 0.597
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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