Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa1226Putative Na+/H+ antiporter; Function of strongly homologous gene; membrane component. (437 aa)    
Predicted Functional Partners:
PSHAa1225
Homologs of previously reported genes of unknown function.
 
     0.668
PSHAb0350
Putative Na+/H+ antiporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
  
   
 0.634
PSHAa0287
Putative mandelate racemase/muconate lactonizing enzyme family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
     
 0.599
PSHAa2223
putativeB12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase (N terminal); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
     
 0.599
phhB
Pterin-4-alpha-carbinolamine dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.548
PSHAa2222
Putative B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase (C terminal); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.540
argE
Acetylornithine deacetylase (Acetylornithinase) (AO) (N-acetylornithinase) (NAO); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.536
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
     
 0.529
mtnB
Putative aldolase or epimerase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.
     
 0.523
metJ
Transcriptional repressor for methionine biosynthesis (MetJ family); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
      
 0.514
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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