STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icdIsocitrate dehydrogenase, specific for NADP+; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (419 aa)    
Predicted Functional Partners:
acnA
Aconitate hydratase (likely to be used in stationary phase); Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.983
acnB
Bifunctional protein [Includes: aconitate hydratase 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aconitase/IPM isomerase family.
  
 
 0.977
sucA
2-oxoglutarate dehydrogenase E1 component; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.972
fumB
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.964
PSHAb0465
Probable isopropylmalate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
0.958
PSHAa1727
Isocitrate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the monomeric-type IDH family.
    
 0.922
gdhA
Glutamate dehydrogenase, NADP-specific; Function of strongly homologous gene; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.915
acnA-2
Aconitate hydratase 1; Function of homologous gene experimentally demonstrated in an other organism; carrier.
 
 0.915
mdh
Malate dehydrogenase, NAD(P)-binding; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.914
aspC
Aspartate aminotransferase (Transaminase A) (ASPAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.887
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.