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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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aceK1Putative isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (592 aa)    
Predicted Functional Partners:
icd
Isocitrate dehydrogenase, specific for NADP+; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 
 0.823
aceA
Isocitrate lyase 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.730
PSHAa1306
Putative transcriptional regulator of the LysR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator; Belongs to the LysR transcriptional regulatory family.
 
     0.609
PSHAa1308
Putative quinone oxidoreductase, NADPH-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.539
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
 
  
 0.446
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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