node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dcd | mazG | PSHAa1319 | PSHAa0740 | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | 0.916 |
dcd | metG | PSHAa1319 | PSHAa1317 | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.757 |
dcd | mrp | PSHAa1319 | PSHAa1318 | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Putative ATPase of the MinD/MRP superfamily; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.890 |
dcd | ndk | PSHAa1319 | PSHAb0142 | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.924 |
dcd | nrdA | PSHAa1319 | PSHAa1418 | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.599 |
dcd | pyrG | PSHAa1319 | PSHAa0741 | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.921 |
dcd | thyA | PSHAa1319 | PSHAa0749 | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.785 |
dcd | udk | PSHAa1319 | PSHAb0080 | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.569 |
dcd | uvrD | PSHAa1319 | PSHAa0122 | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | DNA-dependent ATPase I and helicase II; Function of strongly homologous gene; enzyme. | 0.585 |
dcd | uvrD-2 | PSHAa1319 | PSHAa1096 | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | DNA helicase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.585 |
mazG | dcd | PSHAa0740 | PSHAa1319 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.916 |
mazG | ndk | PSHAa0740 | PSHAb0142 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
mazG | nrdA | PSHAa0740 | PSHAa1418 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.623 |
mazG | pyrG | PSHAa0740 | PSHAa0741 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.976 |
mazG | thyA | PSHAa0740 | PSHAa0749 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.632 |
mazG | udk | PSHAa0740 | PSHAb0080 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.902 |
metG | dcd | PSHAa1317 | PSHAa1319 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.757 |
metG | mrp | PSHAa1317 | PSHAa1318 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Putative ATPase of the MinD/MRP superfamily; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.866 |
metG | pyrG | PSHAa1317 | PSHAa0741 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.621 |
mrp | dcd | PSHAa1318 | PSHAa1319 | Putative ATPase of the MinD/MRP superfamily; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.890 |