| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1343 | PSHAa1344 | PSHAa1343 | PSHAa1344 | Putative oxoacyl-(acyl carrier protein) reductase with NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Homologs of previously reported genes of unknown function. | 0.575 |
| PSHAa1343 | sohB | PSHAa1343 | PSHAa1345 | Putative oxoacyl-(acyl carrier protein) reductase with NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Protease (may metabolize cleaved signal peptides); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.429 |
| PSHAa1344 | PSHAa1343 | PSHAa1344 | PSHAa1343 | Homologs of previously reported genes of unknown function. | Putative oxoacyl-(acyl carrier protein) reductase with NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.575 |
| PSHAa1344 | sohB | PSHAa1344 | PSHAa1345 | Homologs of previously reported genes of unknown function. | Protease (may metabolize cleaved signal peptides); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.583 |
| sohB | PSHAa1343 | PSHAa1345 | PSHAa1343 | Protease (may metabolize cleaved signal peptides); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative oxoacyl-(acyl carrier protein) reductase with NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.429 |
| sohB | PSHAa1344 | PSHAa1345 | PSHAa1344 | Protease (may metabolize cleaved signal peptides); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Homologs of previously reported genes of unknown function. | 0.583 |
| sohB | topA | PSHAa1345 | PSHAa1348 | Protease (may metabolize cleaved signal peptides); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...] | 0.441 |
| sohB | trpCF | PSHAa1345 | PSHAa1290 | Protease (may metabolize cleaved signal peptides); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Bifunctional: indole-3-glycerolphosphate synthetase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. | 0.445 |
| sohB | zipA | PSHAa1345 | PSHAa1082 | Protease (may metabolize cleaved signal peptides); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative Cell division protein zipA homolog; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.448 |
| topA | sohB | PSHAa1348 | PSHAa1345 | DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...] | Protease (may metabolize cleaved signal peptides); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.441 |
| topA | trpCF | PSHAa1348 | PSHAa1290 | DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...] | Bifunctional: indole-3-glycerolphosphate synthetase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. | 0.455 |
| topA | zipA | PSHAa1348 | PSHAa1082 | DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...] | Putative Cell division protein zipA homolog; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.403 |
| trpCF | sohB | PSHAa1290 | PSHAa1345 | Bifunctional: indole-3-glycerolphosphate synthetase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. | Protease (may metabolize cleaved signal peptides); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.445 |
| trpCF | topA | PSHAa1290 | PSHAa1348 | Bifunctional: indole-3-glycerolphosphate synthetase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. | DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...] | 0.455 |
| zipA | sohB | PSHAa1082 | PSHAa1345 | Putative Cell division protein zipA homolog; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | Protease (may metabolize cleaved signal peptides); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.448 |
| zipA | topA | PSHAa1082 | PSHAa1348 | Putative Cell division protein zipA homolog; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...] | 0.403 |