Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
edd6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (617 aa)    
Predicted Functional Partners:
agaI
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 0.998
eda
Multifunctional: 2-keto-3-deoxygluconate 6-phosphate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.998
PSHAa1744
Putative 4-hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
 0.991
idnK
Putative D-gluconate kinase active at low temperature (idonate catabolism); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.941
zwf
Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1. 49) (G6PD); Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
  
 0.938
PSHAa1407
Putative gluconate-6-phosphate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 0.926
PSHAa1745
Putative ketodeoxygluconokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
    
 0.906
glk
Putative glucokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the bacterial glucokinase family.
 
  
 0.903
epd-2
Glyceraldehyde 3-phosphate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.835
ilvH
Acetolactate synthase isozyme III small subunit; Function of strongly homologous gene; enzyme.
 
 
 0.747
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: medium (50%) [HD]