| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1333 | PSHAa1419 | PSHAa1333 | PSHAa1419 | Putative PTS system protein (partial match); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy. | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.901 |
| PSHAa1333 | anmK | PSHAa1333 | PSHAb0124 | Putative PTS system protein (partial match); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy. | Putative molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.902 |
| PSHAa1419 | PSHAa1333 | PSHAa1419 | PSHAa1333 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative PTS system protein (partial match); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy. | 0.901 |
| PSHAa1419 | PSHAa1814 | PSHAa1419 | PSHAa1814 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function of strongly homologous gene; enzyme. | 0.673 |
| PSHAa1419 | PSHAa2631 | PSHAa1419 | PSHAa2631 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Homologs of previously reported genes of unknown function. | 0.965 |
| PSHAa1419 | anmK | PSHAa1419 | PSHAb0124 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.902 |
| PSHAa1419 | aroA | PSHAa1419 | PSHAa1423 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.638 |
| PSHAa1419 | gyrA | PSHAa1419 | PSHAa1421 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | DNA gyrase, subunit A, type II topoisomerase; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP- [...] | 0.601 |
| PSHAa1419 | nrdA | PSHAa1419 | PSHAa1418 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.453 |
| PSHAa1419 | purL | PSHAa1419 | PSHAa2330 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Phophoribosylformylglycinamidine synthase (FGAM synthetase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.447 |
| PSHAa1419 | serC | PSHAa1419 | PSHAa1422 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.678 |
| PSHAa1419 | ubiG | PSHAa1419 | PSHAa1420 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Bifunctional: 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.871 |
| PSHAa1814 | PSHAa1419 | PSHAa1814 | PSHAa1419 | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function of strongly homologous gene; enzyme. | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.673 |
| PSHAa2631 | PSHAa1419 | PSHAa2631 | PSHAa1419 | Homologs of previously reported genes of unknown function. | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.965 |
| anmK | PSHAa1333 | PSHAb0124 | PSHAa1333 | Putative molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Putative PTS system protein (partial match); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy. | 0.902 |
| anmK | PSHAa1419 | PSHAb0124 | PSHAa1419 | Putative molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.902 |
| aroA | PSHAa1419 | PSHAa1423 | PSHAa1419 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.638 |
| aroA | gyrA | PSHAa1423 | PSHAa1421 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | DNA gyrase, subunit A, type II topoisomerase; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP- [...] | 0.699 |
| aroA | serC | PSHAa1423 | PSHAa1422 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.947 |
| aroA | ubiG | PSHAa1423 | PSHAa1420 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Bifunctional: 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.644 |