Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrCPeptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (427 aa)    
Predicted Functional Partners:
dipZ
Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
   
 
 0.943
msrB
Peptide methionine-R-sulfoxide reductase, MsrB protein (PilB protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
0.872
ccmG
Thiol:disulfide interchange protein dsbE (cytochrome c biogenesis protein ccmG); Function of strongly homologous gene; enzyme.
   
 0.856
PSHAb0131
Putative thioredoxin family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
   
 0.856
dsbE
Putative thiol:disulfide interchange protein; Function of strongly homologous gene; enzyme.
   
 0.856
PSHAa1896
Homologs of previously reported genes of unknown function.
  
    0.831
polA
Multifunctional DNA polymerase I: 5'->3' exonuclease (N-terminal); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.737
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.734
PSHAa1138
Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 
 0.689
PSHAb0231
Mercuric reductase (Hg(II) reductase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
  
 0.672
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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