Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa1452Isovaleryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (391 aa)    
Predicted Functional Partners:
PSHAa1451
Beta subunit of a coenzyme A carboxylases family protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
PSHAa1449
Urea carboxylase (alpha subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.988
fadB
Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 0.981
fadJ
Fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family. In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 0.981
etfA
Electron transfer flavoprotein alpha subunit; Function of homologous gene experimentally demonstrated in an other organism.
 
 0.979
paaF
Putative enoyl-CoA hydratase-isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.958
PSHAa1450
Putative enoyl-CoA hydratase/isomerase; Function of strongly homologous gene; enzyme.
 
 0.939
hmgcL
Hydroxymethylglutaryl-CoA lyase (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.933
dbT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
  0.917
PSHAa1453
Putative Transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator.
 
    0.841
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.