Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa14593-hydroxyisobutyrate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the HIBADH-related family. (315 aa)    
Predicted Functional Partners:
PSHAa1458
Enoyl-CoA hydratase/isomerase family protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.998
PSHAa1457
Enoyl-CoA hydratase/carnithine racemase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.
 
  
 0.995
PSHAa1455
Methylmalonate-semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.984
PSHAa1456
Acyl-CoA dehydrogenase family protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.915
PSHAa1460
Putative 3-oxoacyl-(acyl-carrier protein) reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
     
 0.864
acs
Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.837
prpE
Propionyl CoA synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.837
prpC
Methylcitrate synthase (citrate synthase 2); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
  
 
 0.817
dbT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.810
yhdH
Putative dehydrogenase, NAD(P)-binding domain and GroES-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
     
  0.800
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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