Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pgmPhosphoglucomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (545 aa)    
Predicted Functional Partners:
pgi
Glucosephosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.
 
 0.987
tktA
Transketolase 1 (TK 1); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.934
galU
UTP-glucose-1-phosphate uridylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.934
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
 
 0.920
glk
Putative glucokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the bacterial glucokinase family.
     
 0.919
seqA
SeqA protein, recognizes hemimethylated GATC motifs; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
 
    0.917
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily.
  
 0.913
zwf
Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1. 49) (G6PD); Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 0.911
PSHAa1333
Putative PTS system protein (partial match); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
    
  0.908
PSHAa2966
Homologs of previously reported genes of unknown function; Belongs to the glucose-6-phosphate 1-epimerase family.
     
 0.907
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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