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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa1638Homologs of previously reported genes of unknown function. (92 aa)    
Predicted Functional Partners:
fldA
Flavodoxin 1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
 
  
 0.969
seqA
SeqA protein, recognizes hemimethylated GATC motifs; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
 
    0.894
PSHAa1637
Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
       0.868
fur
Ferric uptake regulation protein; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the Fur family.
      0.847
ilvM
Acetolactate synthase II, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
     0.774
PSHAa1818
Homologs of previously reported genes of unknown function; Belongs to the UPF0352 family.
  
    0.771
PSHAa1636
Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
       0.759
gsk
Inosine-guanosine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
     0.747
PSHAa0124
Conserved protein of unknown function (similar to E. coli YacL); Homologs of previously reported genes of unknown function.
  
     0.686
ccmD
Heme exporter protein D (Cytochrome c-type biogenesis protein ccmD); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
  
     0.679
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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