Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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sucBDihydrolipoyltranssuccinate transferase, component of the 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (512 aa)    
Predicted Functional Partners:
sucA
2-oxoglutarate dehydrogenase E1 component; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.999
sucD
succinyl-CoA synthetase, alpha subunit, NAD(P)-binding; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.995
lpd
Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.994
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.991
bkdA2
2-oxoisovalerate dehydrogenase E1 component beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.988
PSHAa0758
Putative pyridine nucleotide-disulfide oxidoreductase, class I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
 
 0.978
BckdhA
2-oxoisovalerate dehydrogenase E1 component alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.943
ygfH
propionyl-CoA:succinate-CoA transferase; Function of strongly homologous gene; enzyme.
   
 0.915
sdhB
Succinate dehydrogenase, Fe-S protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.904
aceE
Pyruvate dehydrogenase, decarboxylase subunit, thiamin-binding; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 
 0.870
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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