| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1590 | fumB | PSHAa1590 | PSHAa1166 | 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.829 |
| PSHAa1590 | fumC | PSHAa1590 | PSHAa0048 | 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. | Fumarase C (fumarate hydratase Class II); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.876 |
| PSHAa1590 | gabD | PSHAa1590 | PSHAa2402 | 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. | Succinate-semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.908 |
| PSHAa1590 | sdhA | PSHAa1590 | PSHAa1649 | 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. | Succinate dehydrogenase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.911 |
| PSHAa1590 | sdhB | PSHAa1590 | PSHAa1648 | 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. | Succinate dehydrogenase, Fe-S protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.906 |
| PSHAa1590 | sdhC | PSHAa1590 | PSHAa1651 | 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. | Putative succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with sdhD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.903 |
| PSHAa1590 | sdhD | PSHAa1590 | PSHAa1650 | 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. | Putative succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with sdhC; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.904 |
| PSHAa1590 | sucA | PSHAa1590 | PSHAa1647 | 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. | 2-oxoglutarate dehydrogenase E1 component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.857 |
| fumB | PSHAa1590 | PSHAa1166 | PSHAa1590 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. | 0.829 |
| fumB | fumC | PSHAa1166 | PSHAa0048 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarase C (fumarate hydratase Class II); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.985 |
| fumB | gabD | PSHAa1166 | PSHAa2402 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate-semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.829 |
| fumB | sdhA | PSHAa1166 | PSHAa1649 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.989 |
| fumB | sdhB | PSHAa1166 | PSHAa1648 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase, Fe-S protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.996 |
| fumB | sdhC | PSHAa1166 | PSHAa1651 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Putative succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with sdhD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.988 |
| fumB | sdhD | PSHAa1166 | PSHAa1650 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Putative succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with sdhC; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.984 |
| fumB | sucA | PSHAa1166 | PSHAa1647 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 2-oxoglutarate dehydrogenase E1 component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.810 |
| fumB | sucC | PSHAa1166 | PSHAa1645 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.846 |
| fumB | sucD | PSHAa1166 | PSHAa1644 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase, alpha subunit, NAD(P)-binding; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.791 |
| fumC | PSHAa1590 | PSHAa0048 | PSHAa1590 | Fumarase C (fumarate hydratase Class II); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. | 0.876 |
| fumC | fumB | PSHAa0048 | PSHAa1166 | Fumarase C (fumarate hydratase Class II); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.985 |