| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1664 | PSHAa1666 | PSHAa1664 | PSHAa1666 | Putative orphan protein; No homology to any previously reported sequences. | Homologs of previously reported genes of unknown function. | 0.873 |
| PSHAa1664 | rlmL | PSHAa1664 | PSHAa1667 | Putative orphan protein; No homology to any previously reported sequences. | Putative methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.846 |
| PSHAa1664 | uup | PSHAa1664 | PSHAa1665 | Putative orphan protein; No homology to any previously reported sequences. | Putative ABC transporter, ATP_binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy. | 0.885 |
| PSHAa1664 | ycbW | PSHAa1664 | PSHAa1668 | Putative orphan protein; No homology to any previously reported sequences. | Putative orphan protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | 0.764 |
| PSHAa1666 | PSHAa1664 | PSHAa1666 | PSHAa1664 | Homologs of previously reported genes of unknown function. | Putative orphan protein; No homology to any previously reported sequences. | 0.873 |
| PSHAa1666 | rlmL | PSHAa1666 | PSHAa1667 | Homologs of previously reported genes of unknown function. | Putative methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.852 |
| PSHAa1666 | uup | PSHAa1666 | PSHAa1665 | Homologs of previously reported genes of unknown function. | Putative ABC transporter, ATP_binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy. | 0.880 |
| PSHAa1666 | ycbW | PSHAa1666 | PSHAa1668 | Homologs of previously reported genes of unknown function. | Putative orphan protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | 0.774 |
| rlmL | PSHAa1664 | PSHAa1667 | PSHAa1664 | Putative methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Putative orphan protein; No homology to any previously reported sequences. | 0.846 |
| rlmL | PSHAa1666 | PSHAa1667 | PSHAa1666 | Putative methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Homologs of previously reported genes of unknown function. | 0.852 |
| rlmL | uup | PSHAa1667 | PSHAa1665 | Putative methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Putative ABC transporter, ATP_binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy. | 0.869 |
| rlmL | ycbW | PSHAa1667 | PSHAa1668 | Putative methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Putative orphan protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | 0.800 |
| rplC | rplD | PSHAa0144 | PSHAa0145 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.999 |
| rplC | rplM | PSHAa0144 | PSHAa2532 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
| rplC | rplU | PSHAa0144 | PSHAa2656 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.995 |
| rplC | rpsC | PSHAa0144 | PSHAa0150 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.999 |
| rplC | rpsO | PSHAa0144 | PSHAa1000 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.995 |
| rplC | uup | PSHAa0144 | PSHAa1665 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Putative ABC transporter, ATP_binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy. | 0.706 |
| rplD | rplC | PSHAa0145 | PSHAa0144 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.999 |
| rplD | rplM | PSHAa0145 | PSHAa2532 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.998 |