STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crcBProtein crcB homolog; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (101 aa)    
Predicted Functional Partners:
serS
Serine tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
       0.890
rarA
Putative polynucleotide enzyme with nucleotide triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
       0.815
lolA
Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
       0.815
PSHAa1716
Putative cell division protein with DNA segregation ATPase FtsK/SpoIIIE domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
       0.815
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
     
 0.789
lrp
Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein; Function of strongly homologous gene; regulator.
  
    0.724
PSHAa1718
Alanine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the AlaDH/PNT family.
       0.684
proC
Pyrroline-5-carboxylate reductase (NAD(P)-binding); Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
  
 0.665
glpF
Putative glycerol diffusion channel; Function of strongly homologous gene; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family.
      
 0.619
mdtI
Putative multidrug transport protein (SmR superfamily); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
     
 0.549
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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