Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pabC4-amino-4-deoxychorismate lyase; Function of strongly homologous gene; enzyme. (274 aa)    
Predicted Functional Partners:
mltG
Conserved protein of unknown function; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
 
  
 0.989
pabB
Aminodeoxychorismate synthase subunit I, component of p-aminobenzoate synthase multienzyme complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.968
pabA
Putative glutamine amidotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
 
 0.955
folP
Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.948
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
  
 0.946
holB
Putative DNA polymerase III delta' subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
  
 0.898
PSHAa1800
Putative metallo-dependent hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
    0.894
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 0.871
pilZ
Type 4 fimbrial biogenesis protein PILZ; Function of strongly homologous gene.
       0.847
birA
Biotin-[protein] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
  
 0.778
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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