Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PSHAa1823Homologs of previously reported genes of unknown function. (147 aa)    
Predicted Functional Partners:
PSHAa0953
Putative anti-sigma factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; factor; Belongs to the anti-sigma-factor antagonist family.
   
  
 0.662
bfr
Bacterioferritin (Cytochrome B-1) (Cytochrome B-557); Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
   
  
 0.563
bfr-2
Bacterioferritin (Cytochrome B-1) (Cytochrome B-557); Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
   
  
 0.563
PSHAa2964
Homologs of previously reported genes of unknown function.
  
    0.537
PSHAa1822
Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator; Belongs to the LysR transcriptional regulatory family.
       0.468
PSHAa2218
Homologs of previously reported genes of unknown function; Belongs to the UPF0337 (CsbD) family.
  
  
 0.452
aceK2
Putative isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
       0.440
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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