Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa1826Putative sigma factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; factor; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)    
Predicted Functional Partners:
PSHAa1825
Putative transmembrane sensor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
 
 
 0.972
rseA
Putative anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), wh [...]
  
 
 0.951
PSHAa1824
Putative ferric enterobactin receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
 
    0.696
PSHAa1862
Putative TonB-dependent receptor; Function of homologous gene experimentally demonstrated in an other organism; receptor.
  
  
 0.668
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.625
PSHAa0125
Homologs of previously reported genes of unknown function.
  
    0.618
rpoC
RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.581
cheR
Chemotaxis protein methyltransferase CheR; Function of homologous gene experimentally demonstrated in an other organism; regulator.
    
 
 0.571
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.564
PSHAa0847
Putative orphan protein; No homology to any previously reported sequences.
 
     0.527
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.