| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1990 | PSHAb0119 | PSHAa1990 | PSHAb0119 | DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.524 |
| PSHAa1990 | dnaN | PSHAa1990 | PSHAa0002 | DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.958 |
| PSHAa1990 | polA | PSHAa1990 | PSHAa2757 | DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Multifunctional DNA polymerase I: 5'->3' exonuclease (N-terminal); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.912 |
| PSHAa1990 | recA | PSHAa1990 | PSHAa0694 | DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.847 |
| PSHAa1990 | recD | PSHAa1990 | PSHAa1857 | DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Exonuclease V, alpha chain with recC and recD: 5' and 3' nuclease, ATPase, recombinase, helicase; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA- [...] | 0.748 |
| PSHAa1990 | recQ | PSHAa1990 | PSHAa2572 | DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.461 |
| PSHAa1990 | sbcD | PSHAa1990 | PSHAb0055 | DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Exonuclease sbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.575 |
| PSHAb0119 | PSHAa1990 | PSHAb0119 | PSHAa1990 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.524 |
| PSHAb0119 | dnaN | PSHAb0119 | PSHAa0002 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.675 |
| PSHAb0119 | polA | PSHAb0119 | PSHAa2757 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Multifunctional DNA polymerase I: 5'->3' exonuclease (N-terminal); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.881 |
| PSHAb0119 | recA | PSHAb0119 | PSHAa0694 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.827 |
| PSHAb0119 | recD | PSHAb0119 | PSHAa1857 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Exonuclease V, alpha chain with recC and recD: 5' and 3' nuclease, ATPase, recombinase, helicase; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA- [...] | 0.661 |
| PSHAb0119 | recQ | PSHAb0119 | PSHAa2572 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.923 |
| PSHAb0119 | sbcD | PSHAb0119 | PSHAb0055 | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Exonuclease sbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.831 |
| dnaN | PSHAa1990 | PSHAa0002 | PSHAa1990 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.958 |
| dnaN | PSHAb0119 | PSHAa0002 | PSHAb0119 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.675 |
| dnaN | polA | PSHAa0002 | PSHAa2757 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Multifunctional DNA polymerase I: 5'->3' exonuclease (N-terminal); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.991 |
| dnaN | recA | PSHAa0002 | PSHAa0694 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.925 |
| dnaN | recD | PSHAa0002 | PSHAa1857 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exonuclease V, alpha chain with recC and recD: 5' and 3' nuclease, ATPase, recombinase, helicase; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA- [...] | 0.821 |
| dnaN | recQ | PSHAa0002 | PSHAa2572 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.675 |
