Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cpoBPutative periplasmic protein contains a protein prenylyltransferase domain; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (248 aa)    
Predicted Functional Partners:
tolB
Required for outer membrane integrity, uptake of group A colicins, and translocation of phage DNA; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 0.995
pal
Required for outer membrane integrity, uptake of group A colicins, and translocation of phage DNA; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 0.971
tolQ
Tol-Pal system protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
  
 0.920
tolR
Biopolymer transport protein TolR; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
  
 0.840
PSHAa1872
Putative TolA protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
 
   0.811
surA
Peptidyl-prolyl cis-trans isomerase (PPIase); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
 
   0.610
PSHAa0183
Putative outer membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
 
  
 0.599
ppiD
Peptidyl-prolyl cis-trans isomerase D (PPIase D) (Rotamase D); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   0.590
tolC
Outer membrane protein tolC precursor; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
     0.576
PSHAa0629
Homologs of previously reported genes of unknown function.
 
  
 0.569
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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